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急性骨髄性白血病(AML)のため,Ara—C療法中の41歳の女性が視力障害を主訴に眼科を受診し,白血病性網膜症と診断した。HLA適合血小板輸血により出血は徐々に改善し,2年を経た現在,完全寛解中であり,良好な視力RV=0.3LV=1.0を回復した。重篤な網膜症は予後不良という報告が多い。本症例は,白血病性網膜症より回復した1例である。
A 41-year-old female was treated with high-dose cytarabine (Ara-C) for acute myeloblastic leuke-mia. She developed bilateral acute visual distur-bance 3 weeks after initiation of therapy. She showed typical leukemic retinopathy in both eyes.Corrected visual acuity was 3/100 and 10/100 each. HLA-matched platelet transfusion led to gradual and steady recovery of retinopathy. The corrected visual acuity improved to 6/20 and 20/20 4 months after platelet transfusion. She was in a state of complete remission one year later. The presence of severe retinopathy has been regarded as a poor prognostic sign. The present case is an unusual instance of long-term survival after pronounced leukemic retinopathy.
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