新潟大学眼感染症クリニックでの10年間の検出菌

Incidence of microorganisms isolated from ocular infections during a ten-year period

　1980年から1989年に新潟人学眼感染症クリニックを受診した患者を対象として，菌の検出，薬剤感受性検査を行った。

　1.3,648株が検出され，Gram陽性球菌が55.4％，Gram陰性桿菌が18.1％であった。S．epidermidisが最も多く検出され，Gram陽性球菌の61.6％を占めた。Gram陰性桿菌ではP．aer-uginosaを除く非発酵菌が57.6％と最多であった。

　2．薬剤耐性において，S．epidermidisではPCG,MCIPCで，S．aureusではPCG，ABPC，MCIPC，CEZ，EM，CLDMで増加傾向を示した。1989年ではP．aeruginosaでIPM,AMK,OFLXに，H．influenzaeでIPM,AMK,MINO,OFLXに，非発酵菌でMINO, OFLXにおいて耐性株を認めなかった。

We reviewed the incidence and drug sensitivity of microorganisms in 2,472 patients in our department over a 10-year period, 1980-89. A total of 3,648 strains were isolated. Gram-positive cocci were the most frequent at 55.4%, followed by Gram-negative rods at 18.1%. Staphylococcus epidermidis comprised 61.8% of Gram-positive cocci. Among Gram-nega-tive rods, nonfermentative Gram-negative rods were most frequent at 57.6%. S. epidermidis and S. aureus were generally sensitive to AMK, MINO and OFLX and were resistant to PCG, ABPC, EM and CLDM. Nonfermentative Gram-negative rods were generally sensitive to IPM, MINO and OFLX and were resistant to ABPC, CEZ and AMK. H. influenzae was sensitive to IPM, AMK, MINO and OFLX.