Wegener's granulomatosisの1症例

A case of Wegener's granulomatosis

　胸部病変と腎病変を有し，強角膜潰瘍を発症した44歳男性のWegener's granulomatosisを経験した。眼科的な初発症状は，結膜炎，上強膜炎，角膜炎，ぶどう膜炎で，やがて強角膜潰瘍に進行した。この症例に対し，開胸生検を行い，病理組織学的診断を得た後に，cyclophosphamideの全身投与を行い，劇的な症状の改善を認めた。

A 44-year-old male presented with conjun-ctivitis, episcleritis, keratitis and anterior uveitis. Sclerocorneal ulcer developed later. He was also affected by pulmonal and renal lesions. Open-lungbiopsy led to the diagnosis of Wegener's granulomatosis. Systemic treatment with cyclo-phosphamide resulted in remarkable improvement in the ocular lesions.