Central bitemporal hemianopsia masqueraded in a case of ethambutol toxicity Michiko Mandai 1 , Nagahisa Yoshimura 1 , Yosihito Honda 1 , Yosio Sumida 2 1Dept of Ophthalmol Kyoto univ 2Sumida Eve Clinic pp.1124-1127
Published Date 1990/7/15
DOI https://doi.org/10.11477/mf.1410900290
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A 82-year-old male showed a decrease in visual acuity to 0.6 in the right eye and 0.2 in the left with correction. He presented decreased central fusion frequency, abnormal color vision simulating tritanopia and central bitemporal hemianopsia. Space-occupying lesion in the central nervous sys-tem was ruled out by computed tomography and magnetic resonance imaging. Later it was revealed that he had been under treatment with oral etham-butol at the dosis of 1 g daily during the foregoing 11 months.

Spontaneous recovery of visual acuity set in 3 months later. The visual field also recovered another 3 months later.

Ethambutol may affect the optic tract either diffusely or focally. In either instance, the papil-lomacular bundle appears to be more liable to damage resulting, as in this case, in central hemitemporal hemianopsia.

Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.


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