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A case of choroidal neovascularization following fungal retinochoroiditis Tamami Mimoto 1 , Akihiko Shiraki 2 , Maiko Yoshioka 1 , Seiji Kitamura 1 , Kazuichi Maruyama 3 , Misako Tatebayashi 1 1Department of Ophthalmology, Kinki Central Hospital 2Department of Ophthalmology, Graduate School of Medicine, Osaka University 3Department of Vision Informatics, Graduate School of Medicine, Osaka University pp.1084-1089
Published Date 2022/8/15
DOI https://doi.org/10.11477/mf.1410214470
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Abstract Purpose:We report a case of choroidal neovascularization(CNV)following fungal retinochoroiditis.

Case:A 77-year-old man developed fungemia due to Candida albicans during treatment for acute pancreatitis and was referred to our department.

Findings and clinical course:At the first visit, visual acuity was 0.8 in the right eye and 0.7 in the left eye and no abnormal findings were observed. However, at the time of re-examination one week later, the onset of fungal retinochoroiditis was confirmed, and treatment with an antifungal drug was initiated. Two months after the end of antifungal administration, a lesion was suspected for recurrence of fungal retinochoroiditis on the optical coherence tomography(OCT). Therefore, we resumed administration of antifungal drug, but no reduction in lesion was obtained. After 3 weeks, complications of cystic macular edema(CME)was observed and CNV was confirmed by fluorescein angiography and OCT angiography, so intravitreal injection of ranibizumab(IVR)was performed and the lesion reduced and CME disappeared. 7 weeks after the first IVR, he underwent a second IVR because of CME recurrence, and he has not seen a recurrence of the lesion until now 4 months later.

Conclusion:For the development of CNV associated with fungal retinochoroiditis, evaluation by OCT is important, and anti-VEGF treatment is considered to be effective.


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