眼皮膚白皮症に角膜内血腫を合併した1例

Intracorneal hematoma in a case of oculocutaneous albinism

要約　目的：眼皮膚白皮症に角膜内血腫を合併した症例の報告。

症例：66歳，男性。生来最高矯正視力は両眼0.1。左眼視力低下にて当院を紹介された。初診時，矯正視力は右0.1，左0.02，両眼の虹彩血管と右眼脈絡膜血管が透見され，全身の皮膚と毛髪に色素脱失がみられたため，眼皮膚白皮症と診断した。左眼角膜実質内の2/3の範囲に血腫を認めた。血腫の吸収に伴い実質内に血管侵入がみられ，強角膜炎に続発した病変と考えてステロイド点眼薬を追加した。2か月後に角膜内血腫は吸収され，新生血管も消退した。

結論：眼皮膚白皮症に角膜内血腫を合併した稀な症例を経験した。

Abstract　Purpose：To report intracorneal hematoma in a case of oculocutaneous albinism.

Case：A 66-year-old male was referred to us under the diagnosis of hyphema in the left eye. He had reportedly best visual acuity of 0.1 in either eye since childhood. He had received surgery for intracranial lymphoma followed by medication.

Findings and Clinical Course：Corrected visual acuity was 0.1 right and 0.02 left. Both eyes showed pendular nystagmus. He showed findings consisting with the diagnosis of oculocutaneous albinism. The left eye showed hematoma including the lower two-thirds of the cornea. The hematoma appeared to be secondary to sclerokeratitis. The left eye was treated by instillation of betamethasone ophthalmic solution. Hematoma was absorbed 5 months later.

Conclusion：The present case of oculocutaneous albinism showed intracorneal hematoma as an unusual complication.