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要約 目的:ぶどう膜炎に続発した緑内障の臨床像と治療方法の調査。
対象と方法:2010年10月〜2014年9月に山口大学医学部附属病院眼科ぶどう膜外来を初診したぶどう膜炎患者171例を後ろ向きに調査した。
結果:ぶどう膜炎続発緑内障の発症率は22.8%,内訳は,炎症による続発緑内障53.8%,ステロイド緑内障46.2%であった。炎症群は前眼部ぶどう膜炎,ステロイド群は全身疾患に随伴したぶどう膜炎が多く,それぞれ,抗炎症治療,ステロイドの減量や中止,抗緑内障薬の点眼や内服,手術により加療された。
結論:ぶどう膜炎続発緑内障は炎症による続発緑内障とステロイド緑内障がほぼ同数にみられ,続発緑内障の原因に応じた治療が必要であった。
Abstract Purpose: To present a review of therapeutic modalities and their outcome for glaucoma secondary to uveitis.
Cases and Method: This retrospective study was made on 171 new patients who were diagnosed with uveitis at the Yamaguchi University Hospital during the past 4 years.
Results: Glaucoma was present or developed in 39 cases(22.8%). Glaucoma was related to intraocular inflammation in 21 cases(53.8%)and to corticosteroid in 18 cases(46.2%). Glaucoma related to intraocular inflammation was more frequent in cases of anterior uveitis. Corticosteroid glaucoma was more frequent in uveitis associated with systemic manifestations. Patients were treated by anti-inflammatory measures, reduction or withdrawal of corticosteroid, topical or systemic use of antiglaucoma agents, or surgical intervention according to the causative factors.
Conclusion: Glaucoma in patients with uveitis was equally due to intraocular inflammation and use of corticosteroid. The patients needed treatments according to the causative factors.
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