松山赤十字病院眼科における眼部悪性腫瘍の検討

A ten-year review of ocular malignancy at Matsuyama Red Cross Hospital

要約　目的：過去10年間の松山赤十字病院眼科で確定診断した眼部悪性腫瘍の報告。対象と方法：2014年11月までの128か月間に病理学的に診断した眼部腫瘍773例を対象とした。年齢別の頻度，腫瘍の悪性度，治療法，転帰などを検索した。結果：悪性腫瘍は186例（24.1％），良性腫瘍は587例（75.9％）であり，悪性腫瘍は高齢者に多かった。眼瞼の悪性腫瘍は，基底細胞癌，脂腺癌，扁平上皮癌の順に多く，結膜の悪性腫瘍は，悪性リンパ腫，扁平上皮癌，悪性黒色腫の順に多かった。眼窩の悪性腫瘍では悪性リンパ腫が最も多かった。眼内腫瘍では，中年者の悪性黒色腫と乳幼児の網膜芽細胞腫が多かった。結論：高齢になるほど悪性腫瘍が増え，予後不良な症例が少なくなかった。

Abstract.　Purpose：To present a ten-year review of ocular malignancy diagnosed at the Department of Ophthalmology, Matsuyama Red Cross Hospital. Cases and Method：This study was made on 773 cases of ocular malignancy who were diagnosed histopathologically during 128 months through November 2014. These cases were evaluated regarding age, degree of malignancy, method of treatment, and outcome. Results：The series comprised 186 cases（24.1％）of malignant tumor and 587 cases（75.9％）of benign tumor. Malignant tumor became more frequent in persons over 50 years of age. Among malignancy of eyelid, basal cell carcinoma was the most frequent, followed by sebaceous cell carcinoma and squamous cell carcinoma. Among malignancy of the conjunctiva, malignant lymphoma was the most frequent followed by squamous cell carcinoma and malignant melanoma. Malignant lymphoma was the most frequent among orbital malignancy. Among intraocular tumors, malignant melanoma and retinoblastoma were the most frequent in middle-aged persons and infants respectively. Conclusion：Ocular malignancy became more frequent in persons of advanced age, including cases with poor outcome.