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Swinging fiashlight test (SFT)によるrelative afferent pupillary dcfect (RAPD)の検出能を再検討するため,視機能上種々の程度の左右差を有する外傷性視神経症,緑内障,視交叉症候群,虚血性視神経症の計35症例について,RAPDの程度と視力,視野,中心フリッカー値(CFF)との関係を調べた.その結果,RAPDと左右眼の視力差との間に関連は認められなかったが,RAPDと左右眼のCFF差には相関があり,患眼のCFFとRAPDと同じ濃度のND filterを負荷した後の他眼のCFFとはよく一致していた.また,視野の量的左右差はGoldmann視野測定の結果から対数閾値を求めて比較したが,I1,I2,I3イソプターの総和とRAPDとの間に強い関連性が認められ,Peritestによる中心視野内の閾値低下の程度,範囲に対応していた.今回の研究結果をopen loop 下のRAPDの分析結果と比較することはできないが,SFTも基本的には中心視野に対応する第3ニューロンの視感度閾値の差を量的にとらえるものと考えられる.
We evaluated the value of relative afferent pupil-lary defect (RAPD) as measured by swinging flash-light test in 35 cases with various optic nerve lesions including glaucoma, pituitary tumor, trauma to the optic nerve and ischemic optic neuropathy. We compared quantified RAPD with other standard indicators of visual function.
There was no significant correlation between RAPD and visual acuity. A close relationship existed between RAPD and critical flicker fusion frequency (CFF). It was generally possible to reciprocate the CFF pattern in the affected eye by placing a neutral density filter before the fellow, intact eye. While RAPD was proportional to the extent of impaired CFF or visual field, the amount of RAPD was most clearly correlated with the depth or volume of the central visual field and the foveal threshold. The latter values could be measured either by Goldmann perimeter or suprathreshold static perimeter.
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