再発をくり返した悪性結膜メラノームの1例について

A Case of Recurrent Malignant Conjunctival Melanoma

緒　言

　外国では皮膚悪性メラノーム，結膜，ブドウ膜悪性メラノームの症例が多いため，メラノームに関する臨床的，実験的研究が多数報告され，螢光抗体法による研究も少なくない。本邦では眼科領域におけるメラノームの螢光抗体法による観察は少ないと思われるのでここに報告する。

We treated a 67-year-old male patient with malignant conjunctival melanoma involving the bulbar and palpebral conjunctiva with repeated recurrence during the 5-year period. Histologi-cal features were characterized by combined presence of spindle and epithelioid cell types.

Excised melanoma was fixed in cold alcohol and was then embedded in paraffin. We car-ried out immunofluorescent stainings with pati-ent's serum, serum of a patient with malignant skin melanoma, antiserum against carcinoemb-ryonic antigen and malignant choroidal melano-ma.