Waldenström's Macroglobulinemiaにおける眼球の組織学的所見

HISTOLOGICAL EXAMINATION ON WALDENSTRÖM'S MACROGLOBULINEMIA

緒言

　1944年，Waldenström^17）はMacroglobuli—nemiaについて最初の報告をし，その第1例には網膜出血を，第2例には網膜中心静脈閉塞症をみている。以来本症のさいの網膜症の病像およびその発生機序に関して多くの検索がなされているが，一方本症を含めたいわゆるHyperviscositysyndromeの血管病変についての議論も少なくない。1967年，教室の土屋ら^13）は本症の臨床像について報告したが，今回同症例の摘出眼球について，組織学的に検索し得たので報告する。

The pathological findings in a case of Wal-denström's macroglobulinemia were descrived, chiefly concerning the retinal vessels.

1) At the periphery of the retina, there were numerous microancurysms with degenerating capillaries. The capillary walls were thickened and the nuclei of the enclotheliums and pericytes were degenerated or absent. At the equator and the posterior, there were degenerated pericytes, so called "ghost cells" in appearance of bea-ding.

2) The vessels of the iris, choroid, and optic nerve were almost normal, apart from PAS-positive materials in their lumina. There were no evidence of venous thrombosis.