水晶体嚢の生化学的研究（第1報）—糖とアミノ酸組成

STUDIES ON SUGAR AND AMINO ACID COMPOSITION IN THE LENS CAPSULE

緒言

　水晶体嚢は水晶体を完全に包被する膜で水晶体上皮細胞より分泌されるものと考えられる^1）。この膜は水晶体の代謝産物の透過を調節する点で重要な働きをもつている。水晶体前嚢は水晶体上皮細胞に接しているが，後嚢は直接水晶体細胞に接している。

　電子顕微鏡的に水晶体嚢はコラーゲン様の線維構造を認めないが，X線回折とヒドロキシプロリンの高い含量からコラーゲン性の膜と考えられている^2）。

Anterior and posterior portions of the lens capsule of calf and cow eyes were obtained free of cellular material by a procedure, which inc-luded ultasonic treatment.

Sugar analyses indicated that approximately 11% of the dry weight of the capsules was in the form of monosaccharide residues, which were identified as glucose, galactose, mannose, fucose, hexosamines, and sialic acids. Small amounts of hexuronic acids were also present. The hexosamines consisted of glucosamine and galactosamine, which were present in the ratios of 92:8 in the calf anterior capsule and 93 : 7 in the calf posterior capsule.