Posner-Schlossman症候群における血液房水柵の変化について

State of blood-aqueous barrier in Posner-Schlossman's syndrome

　Posner-Schlossman症候群の患者12名に対し，寛解期における患眼の血液房水柵の修復を調べる目的で，前眼部フルオロフォトメトリーを施行した．その内10名に対して，螢光虹彩撮影を行った．寛解期における前房内螢光値は，健眼に比べ患眼で，有意に高値を示した（p＜0.005）．しかし，6〜18カ月に及ぶ観察中，4例に血液房水柵の修復を認め，そのいずれもが若年者であった．螢光虹彩撮影では，患眼の80％，健眼の50％に漏出を認め，健眼に比べ患眼での漏出が顕著な例が多かった．若年者では漏出の程度は軽微であった．

　以上より，Posner-Schlossman症候群の患眼での血液房水柵は，特に若年者で，修復されうることが示唆された．血液房水柵の異常の検出には，前眼部フルオロフォトメトリーと螢光虹彩撮影とが有用である．

We evaluated the state of blood-aqueous barrier in 12 pattients with glaucomatocyclitic crisis or Posner-Schlossman's syndrome during the period of remission. We examined all the cases by anterior fluorophotometry and 10 cases by iris angiography.

Fluorescein concentration in the anterior cham-ber was significantly higher in the affected than in the fellow eye in all the cases. The integrity of blood-aqueous barrier in the affected eye became reestablished in 4 young subjects during the follow-up period of 6 to 18 months.

Iris angiography showed extravasation of dye from the iris in 80% of the affected eyes and in 50% of the fellow eyes. The extravasation was invariably more pronounced in the affected than in the fellow eyes. This difference was less apparent in younger subjects.

The findings indicate that the blood-aqueous barrier in glaucomatocyclitic crisis is in an impair. ed state even during the period of remission. The integrity of the barrier may be reestablished, partic-ularly in younger subjects.

Rinsho Ganka (Jpn J Clin Ophthalmol) 42(4) : 359-363, 1988