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要約 目的:トリアムシノロンの硝子体内注入後にサイトメガロウイルス(CMV)網膜炎が発症した1例の報告。症例:8年前に帯状疱疹の既往がある75歳男性が6か月前からの右眼視力低下で受診した。所見:矯正視力は右0.2,左1.0で,右眼に黄斑浮腫を伴う網膜静脈分枝閉塞症があった。トリアムシノロンの硝子体注入を行い,2日後に偽前房蓄膿が生じ,前房と硝子体洗浄を行った。3か月後に前部ぶどう膜炎が生じ,2か月後の硝子体培養でCMVが検出され,CMV網膜炎と診断した。以後5年間の経過は良好で,0.7の最終視力を得ている。結論:免疫正常者であっても,トリアムシノロンの硝子体注入後にCMV網膜炎が発症することがある。
Abstract. Purpose:To report a case of cytomegalovirus retinitis that developed after intravitreal injection of triamcinolone acetonide. Case:A 75-year-old male presented with impaired vision in the right eye since 6 months before. He had a history of herpes zoster 8 years before. Findings:Corrected visual acuity was 0.2 right and 1.0 left. The right eye showed findings of branch retinal vein occlusion with macular edema. He received intravitreal injection of triamcinolone. Pseudohypopyon developed 2 days later and was treated by irrigation of vitreous and anterior chamber. The right eye developed anterior uveitis 3 months later. Cytomegalovirus was cultured from the vitreous leading to the diagnosis of cytomegalovirus retinitis. He has been doing well for 5 years until present with the final visual acuity of 0.7. Conclusion:This case illustrates that cytomegalovirus retinitis may develop in an immunocompetent person following inravitreal injection of triamcinolone acetonide.
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