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A case of keratomycosis caused by Alternaria alternata identified after DNA sequence analysis Satoshi Iwamoto 1 , Toshiyuki Yokoyama 2 , Masataro Hiruma 3 , Ayako Sano 4 , Akira Murakami 1 1Dept of Ophthalmol, Juntendo Univ Sch of Med 2Dept of Ophthalmol, Juntendo Univ Nerima Hosp 3Dept of Dermatol, Juntendo Univ Nerima Hosp 4Dept of Animal Sci, Ryukyu Univ pp.1407-1410
Published Date 2012/9/15
DOI https://doi.org/10.11477/mf.1410104373
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Abstract. Purpose:To report a case of keratomycosis that proved to be due to Alternaria alternata. Case:A 76-year-old male presented with pain and impaired vision in the left eye. He had noticed foreign body sensation in the eye while caring for a miniature tree 3 weeks before. He had been under treatment as iridocyclitis. Findings:Corrected visual acuity was 1.0 right and 0.2 left. The left cornea showed an ill-defined opacity lower and temporal to the vertex. Signs of iritis were present. Smear from the corneal lesion led to the diagnosis of keratomycosis and treatment with topical pimaricin. The corneal lesion was cured leaving scarring 2 weeks later. Analysis of DNA sequence showed the causative organism to be Alternaria alternata. Conclusion:This case illustrates that keratomycosis due to Alternaria alternata may run a benign course as the corneal lesion tends to be confined to the anterior layers only.


Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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