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要約 目的:下眼瞼に異物と肉芽腫が発見され,12年前の外傷が原因と推定された症例の報告。症例:33歳男性が2か月前から増大した右眼の下眼瞼の腫瘤で受診した。所見:下眼瞼の腫瘤は,磁気共鳴画像検査(MRI)で8mm大の結節があり,粉瘤が疑われた。1か月半後に2cm×1cm大の腫瘤を摘出した。病理学的に異物があり,肉芽腫と診断された。巨細胞はなかった。12年前に喧嘩で右眼の下眼瞼に裂傷があり,縫合を2針受けていた。結論:非生物性の異物が組織中に残存すると,刺激性物質として周囲に層状炎症反応を生じ,異物巨細胞による貪食像がない非典型的な異物肉芽腫を形成することがある。本症例は過去の外傷による異物刺入が原因であると推定される。
Abstract. Purpose:To report a case of foreign body granuloma presenting as a tumor in the lower eyelid presumably due to injury 12 years ago. Case:A 33-year-old male presented with a tumor in the right lower eyelid that started to enlarge since 2 months before. Findings:The eyelid tumor appeared as an atheroma by magnetic resonance imaging(MRI). The size of tumor was 2 cm by 1 cm when resected. It was diagnosed with foreign body granuloma by histopathology. No foreign body giant cells were present. Afterwards,the patient revealed a history of traumatic rupture of his lower eyelid 12 years before. Conclusion:Nonbiological foreign body,may cause irritation after prolonged presence in the tissue,and may result in atypical foreign body granuloma surrounded by stratified inflammatory reaction without signs of phagocytosis by giant cells. The eyelid tumor in the present case may have been due to foreign body at the time of injury 12 years before.
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