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要約 目的:横浜市大附属病院眼科(以下,当院)でのぶどう膜炎患者の疫学的検討。対象と方法:2009年4月~2011年3月の間の初診のぶどう膜炎患者について後ろ向きに調査し,当院での過去の調査や全国規模の疫学調査との比較検討を行った。結果:総数427例(男性212例,女性215例)。初診平均年齢51.5歳。サルコイドーシス10.5%,強膜炎9.1%,原田病8.2%,Behçet病7.0%,急性前部ぶどう膜炎6.1%が上位5疾患であった。同定不能例は35.1%で,そのうち45%がサルコイドーシスに類似のぶどう膜炎であった。結論:1990年の当院での調査と比較し,サルコイドーシス,仮面症候群が増加,原田病,Behçet病は減少傾向であった。2003年の全国疫学調査と比較し,上位3疾患や同定不能例の割合は同等であった。
Abstract. Purpose:To present an epidemiological review of endogenous uveitis at Yokohama City University Hospital. Cases and Method:This retrospective study was made on patients who first visited us during 2 years through March 2011. Findings were compared with similar reports in the past. Results:Number of uveitis patients totaled 427 cases. The series comprised 212 males and 215 females. The age averaged 51.5 years when first seen. Uveitis was unilateral in 43% and bilateral in 57% of cases. Sarcoidosis was the most frequent at 10.5%,followed by scleritis 9.1%,Vogt-Koyanagi-Harada(VKH)disease 8.2%,Behçet's disease 7.0%,and acute anterior uveitis 6.1%. Uveitis could not be classified in 35.1% of cases,45% of whom clinical features simulated sarcoidosis. Conclusion:Compared with our survey in 1990,there was an increase of sarcoidosis and masquerade syndrome and a decrease in VKH and Behçet's disease. Incidence of three most frequent entities and of unclassified cases were similar to those of nationwide survey in 2003.
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