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要約 目的:網膜中心静脈閉塞症の長期経過の報告。対象:網膜中心静脈閉塞症がある71例72眼を対象とした。男性37例,女性34例で,初診時の年齢は22~84歳(平均61歳)であった。5~24年(平均9.1年)の経過を追った。結果:治療として汎網膜光凝固を67眼(93%),硝子体手術を11眼(15%),血栓溶解薬を17例(23%)に用いた。眼合併症として,硝子体出血が初診から平均8.5か月,最長3年6か月後に11眼(15%),血管新生緑内障が初診から平均7.6か月,最長2年後に8眼(11%)に生じた。僚眼に網膜静脈分枝閉塞症が5眼,網膜中心静脈閉塞症が3眼に発症した。最終視力は17眼(24%)で改善し,14眼(19%)で不変,41眼(57%)で悪化した。結論:網膜中心静脈閉塞症では発症から4年間は硝子体出血や血管新生緑内障などの重篤な合併症に注意し,僚眼については長期間の経過観察が必要である。
Abstract. Purpose:To report the long-term clinical course of central retinal vein occlusion(CRVO). Cases:This study was made on 72 eyes of 71 cases of CRVO who were followed up for 5 to 24 years,average 9.1 years. The series comprised 37 males and 34 females. The age ranged from 22 to 84 years,average 61 years. Results:Panretinal photocoagulation was performed on 67 eyes(93%),and vitreous surgery on 11 eyes(15%). During the follow-up,vitreous hemorrhage developed in 11 eyes(15%)after an average of 8.5 months and maximally 3 years 6 months. Neovascular glaucoma developed in 8 eyes(11%)after an average of 7.6 months and maximally 2 years. Three cases developed CRVO and 5 cases developed branch retinal vein occlusion in the fellow eye. Final visual acuity improved in 17 eyes(24%),remained unchanged in 14 eyes(19%),and deteriorated in 41 eyes(57%). Conclusion:The present cases show the need to pay particular attention to complications including vitreous hemorrhage and neovascular glaucoma for at least 4 years. The fellow eyes ought to be watched for a long period.
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