緑内障眼における中心角膜厚と眼圧，視野障害との関連―左右眼の比較

Influence of central corneal thickness on intraocular pressure and visual field in bilateral glaucoma

要約　目的：両眼に発症した緑内障眼での中心角膜厚が眼圧と視野に及ぼす影響の報告。対象と方法：広義の原発開放隅角緑内障と診断され，未治療の30例60眼を対象とした。男性7例，女性23例で，年齢は26～77歳（平均50歳）であった。中心角膜厚，24時間眼圧，Humphrey視野障害指数を測定し，左右眼を比較した。結果：中心角膜厚が厚い側と薄い側とで，視野障害指数に有意差はなかった（p＞0.1）。左右眼の中心角膜厚の差と，個々の眼圧値には有意な正の相関があったが（r＝0.4，p＜0.03），視野障害指数には有意な相関がなかった。結論：緑内障眼での中心角膜厚は，眼圧値とは関連するが，視野障害との関連は少ない。

Abstract.　Purpose：To report the influence of central corneal thickness on intraocular pressure（IOP）and visual field in bilaterally affected glaucoma. Cases and Method：This study was performed on 60 eyes of 30 cases who were diagnosed with primary open-angle glaucoma including normal-tension glaucoma before treatment. The series comprised 7 males and 23 females. The age ranged from 26 to 77 years,average 50 years. All the cases received measurement of central corneal thickness,24-hour IOP,and automated perimetry by Humphrey. Results：There was no significant difference in visual field indices between eyes with thinner and thicker central corneal thickness. Difference in corneal thickness between each pair of eyes was significantly correlated with IOP（r＝0.4,p＜0.03）but not with visual field indices. Conclusion：The central corneal thickness is correlated with IOP but not with visual field defect in bilaterally affected glaucoma.