網膜静脈分枝閉塞症に伴う黄斑浮腫に対するベバシズマブ単独治療による視力と光干渉断層計所見

Visual outcome and findings by optical coherence tomography after intravitreal bevacizumab for branch retinal vein occlusion with macular edema

要約　目的：黄斑浮腫を伴う網膜静脈分枝閉塞症にベバシズマブ硝子体投与を行った結果の報告。対象と方法：黄斑浮腫を伴う網膜静脈分枝閉塞症23例23眼を対象とした。年齢は40～81歳（平均64歳）である。6か月以上の経過を観察し，視力と光干渉断層計による中心窩網膜厚を測定した。結果：視力と中心窩網膜厚は投与の1週間後から有意に改善した。12か月後まで改善が持続した6眼（26％）には浮腫の再発がなかった。浮腫が軽減した後，視細胞内節外節接合部が連続している症例では最終時視力が良好であった。結論：黄斑浮腫を伴う網膜静脈分枝閉塞症にベバシズマブ硝子体投与で，視力と中心窩網膜厚が有意に改善した。

Abstract.　Purpose：To report the outcome of intravitreal bevacizumab for branch retinal vein occlusion with macular edema. Cases：This study was made on 23 eyes of 23 patients of branch retinal vein occlusion with macular edema. The age ranged from 40 to 81 years,average 64 years. Cases were followed up for 6 months or longer after treatment regarding visual acuity and foveal thickness measured by optical coherence tomography（OCT）. Results：Visual acuity and foveal thickness started to significantly improve from one week after treatment. There was no recurrence of macular edema in 6 eyes（26％）with persistent improvement for 12 months. Visual acuity at final visit was good in eyes that maintained continuous inner and outer segments of photoreceptors by OCT. Conclusion：Intravitreal bevacizumab was followed by improvement of visual acuity and foveal thickness in eyes of branch retinal vein occlusion with macular edema.