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Nutritional optic neuropathy in a case of pernicious anemia and subacute combined degeneration of the spinal cord Keiko Oe 1 , Toshiyuki Kishi 2 1Dept of Ophthalmol,Takinomiya Gen Hosp 2Dept of Intern Med,Takinomiya Gen Hosp pp.517-520
Published Date 2010/4/15
DOI https://doi.org/10.11477/mf.1410103146
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Abstract. Purpose:To report a case of nutritional optic neuropathy secondary to pernicious anemia and subacute combined degeneration of the spinal cord. Case:A 51-year-old male presented with impaired vision in his right eye since 2 weeks before. He had noticed weakness and numbness in the right upper and lower extremity 2 days before onset of visual disturbance. Findings:Corrected visual acuity was 0.3 right and 0.5 left. The right eye showed relative afferent pupillary defect. Diagnostic imaging of the brain was inconclusive. Systemic studies showed pernicious anemia,vitamin B12 deficiency,and subacute combined degeneration of the spinal cord. Systemic treatment with vitamin B complex and corticosteroid was followed by improved visual acuity of 0.8 in either eye 2 months later. Conclusion:This case was diagnosed with nutritional optic neuropathy secondary to pernicious anemia. There is a possibility that idiopathic optic neuritis may be secondary to vitamin B12 deficiency.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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