Rinsho Ganka Volume 63, Issue 4 (April 2009)

Deficiency optic neuropathy in a case of subacute combined degeneration and Wernicke encephalopathy Yuzhu Chai 1 , Hiroko Yamazaki 1 , Jin Nishimiya 2 , Akihide Iwamura 2 1Dept of Opththalmol,Kohnodai Hosp,Intern Med Cent of Japan 2Dept of Neurol,Gyoutoku Sougou Hosp pp.491-496
Published Date 2009/4/15
DOI https://doi.org/10.11477/mf.1410102664
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Abstract. Purpose:To report deficiency optic neuropathy in a case of subacute combined degeneration and Wernicke encephalopathy. Case:A 67-year-old male presented with impaired vision in both eyes. He had received radiotherapy for lingual cancer and resection of stomach for gastric cancer before. He had felt staggering since one year before. He was in poorly nourished state due to loss of appetite. Findings:Corrected visual acuity was 0.08 right and 0.09 left. Both eyes showed central scotoma. Hematological studies showed vitamin B12 deficiency suggesting subacute combined degeneration. He lost consciousness 2 weeks later. Magnetic resonance imaging led to the diagnosis of Wernicke encephalopathy. Treatment with vitamin B complex resulted in visual acuity of 0.5 in either eye one month later with recovery of visual evoked potential. Conclusion:Nutritional deficiency may be causatively involved in optic neuropathy.

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63巻4号 (2009年4月)
電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院