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Cytomegalovirus retinitis in a case of mixed connective tissue disease Nobuaki Hibi 1 , Kaoru Toyoshima 1 , Makoto Nakamura 2 1Dept of Ophthalmol,Kumiai Kousei Hosp 2Dept of Ophthalmol,Nagoya Univ Grad Sch of Med pp.511-516
Published Date 2010/4/15
DOI https://doi.org/10.11477/mf.1410103145
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Abstract. Purpose:To report a case of mixed connective tissue disease who developed cytomegalovirus(CMV)retinitis. Case:A 47-year-old woman presented with failing vision in her left eye since 2 weeks before. She had been treated with systemic corticosteroid and immunosuppressive drugs for mixed connective tissue disease during the past 5 years. Findings:Her corrected visual acuity was 1.2 right and 0.2 left. Both eyes showed retinal hemorrhage and exudative patches suggestive of retinal vasculitis. CMV was positive in the aqueous humor. She started receiving systemic ganciclovir followed by improved retinal vasculitis. Retinal detachment developed 10 weeks later necessitating vitreous surgery. The left eye developed macular and optic nerve atrophy. The visual acuity is 1.0 right and 0.02 left 23 months after her initial visit. Conclusion:The present case illustrates that CMV may be the underlying cause for retinal vasculitis following systemic treatment with corticosteroid or immunosuppressive agents.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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