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要約 目的:サイトメガロウイルス(CMV)網膜炎から網膜剝離になり,両眼に25ゲージ硝子体手術を行った症例の報告。症例:62歳男性の両眼に数日前から霧視が生じた。両眼に虹彩炎と眼圧上昇があった。加療により消炎し,眼圧が正常化した。初診の3週間後に成人T細胞白血病と診断され,化学療法を開始した。CMV肺炎が複数回起こった。初診の4か月後に左眼の虹彩炎が再発し,血管炎を伴う胞状網膜剝離が生じた。25ゲージ硝子体手術とシリコーンオイル注入で復位が得られ,硝子体液からCMVが検出された。左眼の発症から6か月後に右眼に虹彩炎と網膜炎が生じた。予防の目的で左眼と同様の手術を行い,寛解した。その後両眼に視神経萎縮が生じ,失明した。初診から16か月後に全身状態悪化で死亡した。結論:CMV網膜炎と網膜剝離に対し,25ゲージ硝子体手術が有効であった。
Abstract. Purpose:To report a case of bilateral cytomegalovirus(CMV)uveitis treated with 25-gauge pars plana vitrectomy and silicone oil tamponade. Case:A 62-year-old male presented with blurring in both eyes of few days' duration. Both eyes showed iritis and elevated intraocular pressure(IOP). Treatment was followed by remission in both eyes. He was diagnosed with adult T-cell leukemia 3 weeks later. Chemotherapy was followed by repeated episodes of CMV pneumonia. Iritis recurred in the left eye 4 months after his initial visit. Retinitis progressed to bullous retinal detachment. Remission resulted after 25-gauge pars plana vitrectomy with silicone oil tamponade. Biopsy of vitreous showed CMV. Iritis and retinitis occurred in the right eye another 6 months later. Cure was obtained after similar surgery as the left eye. Both eyes developed optic atrophy with eventual blindness. The patient died of systemic complications 16 months after his initial visit. Conclusion:25-gauge vitrectomy was effective for CMV retinitis and retinal detachment.
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