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Two cases of tubulointerstitial nephritis and uveitis syndrome with fair outcome Hideyasu Mayuzumi 1 , Hideo Akiyama 1 , Tomomi Unno 1 , Kyoichi Takahashi 2 , Junko Hirato 3 , Shoji Kishi 1 1Dept of Ophthalmol,Gunma Univ Sch of Med 2Takahashi Eye Clin 3Dept of Pathol,Gunma Univ Hosp pp.897-901
Published Date 2009/6/15
DOI https://doi.org/10.11477/mf.1410102746
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Abstract. Purpose:To report two cases of tubulointerstitial nephritis and uveitis(TINU)syndrome. Cases:Both were females aged 55 and 21 years respectively. Initial manifestations were bilateral anterior uveitis in one case and fatigue with weight loss in the other. Renal function deteriorated in both cases. Biopsy showed tubulointerstitial nephritis,leading to the diagnosis of TINU syndrome in both cases. Topical and systemic corticosteroid was followed by prompt improvement of uveitis and systemic manifestations including impaired renal function. Conclusion:These cases illustrate that TINU syndrome is preceded by anterior uveitis that frequently responds to treatment. In order not to overlook subsequent TINU syndrome,we advocate repeated hematological examinations in cases of unclassified uveitis.


Copyright © 2009, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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