後期高齢者の緑内障診療における網膜神経線維層厚解析（GDxVCC）の有用性

Value of retinal nerve fiber layer thickness analyzer in the diagnosis of glaucoma in persons over seventy-five years of age

要約　目的：後期高齢者の緑内障診断での網膜神経線維層厚解析の評価。症例と方法：緑内障が疑われた273名544眼にHumphrey視野検査と網膜神経線維層厚解析（GDxVCC）を行った。40～59歳の中高年齢者380眼と，75～100歳の後期高齢者164眼の結果を比較した。結果：信頼できる視野は，中高年齢者の75.3％，後期高齢者の46.3％で得られ，有意差があった（p＜0.001）。信頼できるGDxVCC結果は，それぞれ90.3％と65.9％で得られ，有意差があった（p＜0.001）。緑内障が確定した80眼では，視野の平均偏差とGDxVCCの神経線維指数との間に相関があった（中高年齢者r＝－0.65，後期高齢者r＝－0.68，p＜0.001）。結論：GDxVCCによる網膜神経線維層厚解析は，結果の信頼性が高く，視野と相関し，後期高齢者の緑内障診断に有用である。

Abstract.　Purpose：To report the value of retinal nerve fiber thickness analyzer（GDxVCC）in the diagnosis of glaucoma in senile persons. Cases and Method：This study was made on 544 eyes of 273 persons who were suspected of glaucoma. The series comprised of 2 groups：middle-aged persons（40 to 59 years,380 eyes）and senile persons（75 to 100 years,164 eyes）. All were tested by Humphrey perimetry and GDxVCC. Results：Reliable perimetric data were obtained in 75.3％ of middle-aged and 46.3％ of senile persons. The difference was significant（p＜0.001）. Reliable GDxVCC data were obtained in 90.3％ and 65.9％ respectively. The difference was significant（p＜0.001）. In 80 eyes with definite glaucoma,there was a positive correlation between mean deviation of visual field and nerve fiber parameter by GDxVCC. Conclusion：GDxVCC is useful in the diagnosis of glaucoma in senile persons due to high rate of reliable data.