Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
要約 目的:視力が良好な加齢黄斑変性症に対するベバシズマブ硝子体内注入の効果の報告。対象:加齢黄斑変性症8例8眼を対象とした。男性4例,女性4例で,年齢は51~75歳(平均68歳)である。6眼にはポリープ状脈絡膜血管症,2眼には狭義の加齢黄斑変性症があった。全例で視力は0.5以上であった。ベバシズマブ1.25mgを硝子体内に注入した。結果:6か月以上の経過観察で,7眼で網膜剝離または網膜色素上皮剝離が減少した。脈絡膜新生血管とポリープ状病変は全例で残存した。結論:視力が良好なAMDに対するベバシズマブの硝子体内注入は安全であり,奏効する可能性がある。
Abstract. Purpose:To report the effect of intravitreal injection of bevacizumab for age-related macular degeneration(AMD)in eyes with good visual acuity. Cases and Method:This study was made on 8 eyes of 8 patients of AMD. The series comprised 4 males and 4 females. The age ranged from 51 to 75, average 68 years. Six eyes had polypoidal choroidal vasculopathy and 2 had AMD in its narrow sense. All the eyes had visual acuity of 0.5 or better. Each eye received intraviteral injection of 1.25 mg bevacizumab. Results:During the follow-up for 6 months or longer, 7 eyes showed decrease in retinal detachment or detachment of retinal pigment epithelium when evaluated by fluorescein angiography or optical coherence tomography. Choroidal neovascularization and polypoidal lesion persisted in all the eyes. Conclusion:Intravitreal injection of bevacizumab is safe and potentially effective for AMD with good visual acuity.
Copyright © 2008, Igaku-Shoin Ltd. All rights reserved.