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増殖糖尿病網膜症に対する毛様体【扁】平部経由での硝子体手術後の眼圧上昇を524眼について検索した。172眼では1996~1997年の2年間に,352眼では2001~2004年の4年間に手術が行われた。21mmHg以上の眼圧が術後1か月以降に14日以上続いたものを眼圧上昇と定義した。術後の眼圧上昇は,172眼中26眼(15.1%),352眼中49眼(13.9%)にあり,両群間に有意差はなかった。術前の虹彩ルベオーシスが172眼中26眼(15.1%),352眼中16眼(4.5%)にあり,有意差があった(p<0.01)。眼圧上昇に対する手術件数は,前群より後群で有意に減少した。病態と術式については両群間に差がなかった。後群では黄斑浮腫に対する硝子体手術後の血管新生緑内障が6.2%の頻度で発症した。
We reviewed 524 eyes that received pars plana vitrectomy for proliferative diabetic retinopathy. Vitrectomy was performed during 2 years through 1996 in 172 eyes and during 4 years through 2004 in 352 eyes. We paid particular attention to postoperative elevation of intraocular pressure(IOP). IOP elevation was defined as sustained IOP level more than 21mmHg for 14 days or longer after 1 month of surgery. Postoperative IOP elevation occurred in 26 out of 172 eyes(15.1%)and in 49 out of 352 eyes(13.9%). The difference was not significant. Preoperative rubeosis iridis was present in 26 out of 172 eyes(15.1%)and in 16 out of 352 eyes(4.5%). The difference was significant(p<0.01). Surgery for elevated IOP was significantly less in latter than former group. There was no difference regarding clinical features of retinopathy or surgical approach. Neovascular glaucoma occurred in 6.2% of eyes in the latter group after surgery for macular edema.
Rinsho Ganka(Jpn J Clin Ophthalmol)60(8):1475-1479, 2006
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