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Peroral vitamin A was effective for night blindness in a case of Crohn's disease Yumi Sawada 1 , Kaoru Nakamura 1 , Kumi Sakata 1 , Sadao Hori 1 1Dept of Ophthalmol,Tokyo Women's Med Univ pp.57-60
Published Date 2007/1/15
DOI https://doi.org/10.11477/mf.1410101604
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Abstract. Purpose:To report a case of Crohn's disease with night blindness that was cured by peroral vitamin A. Case:A 38-year-old woman presented with night blindness as chief complaint. She had been diagnosed with Crohn's disease 22 years ago. She was in a state of poor nourishment after improvements and exacerbations of the disease. Her corrected visual acuity was 1.2 in either eye. Funduscopy showed diffuse gray-white spots. Electroretinogram showed severely attenuated a and b waves. Dark adaptation curve was flattened in the first and second phases. Serum level of vitamin A was extremely low. Results:Night blindness disappeared after 2 weeks of treatment with peroral vitamin A. Electroretinogram and dark adaptation became almost normal 5 months later. Gray-white spots in the fundus also disappeared. Conclusion:Night blindness in the present case was apparently due to malabsorption by Crohn's disease. Peroral vitamin A was effective for the night blindness.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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