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要約 目的:Behçet病では,Ⅳ型のほかにⅠ型アレルギーの関与がある可能性がある。Behçet病の発作時と非発作時の血清IgE値を測定し,比較検討した。対象と方法:Behçet病34例で血清IgE値を測定し,うち21例では眼発作時のIgE値を調べた。IgE値はIU/mlで表現した。結果:非発作時のIgE値は0~474,平均86.9±119.7であった。眼発作時に測定した21例のIgE値は,非発作時が平均76.8±110.6,発作時が45.3±62.0であり,有意差があった(p=0.048)。強い眼発作時に測定した6例でのIgE値は,非発作時と有意差がなかった。結論:Behçet病の血清IgE値は,眼発作時には非発作時よりも低下する。
Abstract. Purpose:TypeⅠ allergy may be involved in Behçet disease besides typeⅣ allergy. This paper reports the serum IgE level during and between ocular attacks in Behçet disease. Cases and Methods:This study was made on 34 cases of Behçet disease during a 3 year period. Ocular attacks occurred in 21 cases. IgE level was expressed as IU/ml. Results:IgE level between attacks ranged from 0 to 474,average 86.9±119.7. IgE level in 21 cases averaged 45.3±62.0 during ocular attacks and 76.8±110.6 between attacks. The difference was significant(p=0.048). There was no significant difference in IgE level during and between severe ocular attacks in 6 patients. Conclusion:Serum IgE level decreases during than between ocular attacks.
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