A case of malignant lymphoma with unilateral iris infiltration as the initial manifestation Yumiko Ban 1 , Toshiaki Abe 1 , Kana Takahashi 1 , Makoto Tamai 1 , Takafumi Hasegawa 2 , Ryo Ichinohasama 3 1Dept of Ophthalmol,Tohoku Univ Sch of Med 2Dept of Neurol,Tohoku Univ Grad Sch of Med 3Dept of Oral Pathol,Tohoku Univ Grad Sch of Dentistry pp.363-367
Published Date 2004/3/15
DOI https://doi.org/10.11477/mf.1410100540
  • Abstract
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 A 73-year-old male was diagnosed with anterior uveitis after a piece of mud hit his left eye. Antiinflammatory or antifungal agents were futile. He was referred to us 5 weeks after the incident. His left eye had visual acuity of 0.4 and showed rubeosis iridis with keratic precipiatates. The fundus appeared normal. Biopsy of aqueous humor was performed twice but gave unequivocal findings. He then developed left hemiparesthesia and hemiparesis. Findings by radioisotopes were suggestive of infiltration of malignant tumors into the central nervous system. Biopsy of the iris was performed 5 weeks after his initial visit,leading to the diagnosis of diffuse macrocellular B-cell malignant lymphoma. This case illustrates that malignant lymphoma may show unilateral uveitis with marked iris infiltration as its initial manifestation.

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