Cancer-associated retinopathy in a patient of gallbladder carcinoma Yumiko Ban 1 , Kana Takahashi 1 , Toshitaka Itabashi 1 , Eriko Sugano 1 , Toshiaki Abe 1 , Makoto Tamai 1 1Dept of Ophthalmol,Tohoku Univ Sch of Med pp.2017-2021
Published Date 2004/10/15
DOI https://doi.org/10.11477/mf.1410100779
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 A 80-year-old woman presented with progressive blurring of vision in both eyes since 2months before. She had been diagnosed with asymptomatic gallbladder stone and chronic pancreatitis 5 years before. Her visual acuity was hand motion right and 0.15 left. Funduscopy showed mottled retina,narrowing of vessels,and pigment deposits along the vascular arcades in both eyes. Both eyes showed ring scotoma. Central scotoma was also present in the right eye. Electroretinogram was extinguished. Systemic examinations showed gallbladder carcinoma with metastasis. Western blotting analysis showed 27 kDa antigen to the retina,leading to the diagnosis of cancer-associated retinopathy. To the best of our knowledge,this is the first reported case of cancer-associated retinopathy secondary to gallbladder carcinoma.

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