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Gene Transduction for Experimental Brain Tumors Using Recombinant Adenovirus Vector Tomotsugu Ichikawa 1 , Takashi Tamiya 1 , Yoshiaki Adachi 1 , Yasuhiro Ono 1 , Kengo Matsumoto 1 , Tomohisa Furuta 1 , Takashi Ohmoto 1 , Yoko Yoshida 2 , Hirofumi Hamada 2 1Department of Neurological Surgery, Okayama University Medical School 2Cancer Chemotherapy Center, Japanese Foundation for Cancer Research Keyword: adenovirus , gene therapy , brain tumors , β-galactosidase pp.731-738
Published Date 1998/8/1
DOI https://doi.org/10.11477/mf.1406901322
  • Abstract
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Recent advances in molecular biology have per-mitted significant progress toward the treatment of malignant brain tumors using gene transduction methods. Adenovirus vectors have recently been shown to transduce genes successfully into brain tumor cells both in vitro and in vivo. We have investigated the feasibility of gene transduction for brain tumors using adenovirus vectors.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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