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Coagulation Disorders as Early Predictor of Brain Injury Yoshihiro Takanashi 1 , Masamichi Shinonaga 1 , Eikan Koh 1 , Makoto Naitoh 1 , Isao Yamamoto 2 1Division of Neurosurgery, Hiratsuka Kyosai Hospital 2Department of Neurosurgery, Yokohama City University Keyword: brain injury , fibrin degradation product , prognosis pp.1009-1013
Published Date 1996/11/1
DOI https://doi.org/10.11477/mf.1406901024
  • Abstract
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To identify early prognostic value of brain injury, a comparison was made between computerized tomography (CT) findings, coagulation abnormal-ities, and clinical features in 51 patients with closed head injury. The patients were divided into three groups according to their plasma level of fibrin-fibrinogen degradation product (FDP) : normal group (FDP 10μg/ml or less) in 20 patients ; mode-rately abnormal group (FDP 10-40μg/ml) in 15 patients ; and highly abnormal group (FDP 40/μg/ ml or more) in 16 patients. Cases with a fatal clinical course were mostly associated with very high FDP level.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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