脳性麻痺児の1剖検例

CLINICO-PATHOLOGICAL OBSERVATION OF A INFANTILE CEREBRAL PALSY

Ｉ．はじめに

　脳性麻痺脳髄の病理学的所見は，その病変の多彩さ，病因の多様さによつてさまざまな形態学的変化を示すものであり，その臨床・病理学的所見を個々の症例で詳細に検討することは意味がある。われわれは出産時障害ならびにその後のけいれん障害に起因すると考えられる脳性麻痺児の1例を剖検したので報告する。

A case of female infantile cerebral palsy (13 months) with severe birth injury and convulsive fits is presented. This case is a second baby of identical twins. The first baby had an easy deliveryand developed normally. But the second baby had difficult delivery with asphyxia livida, severe stridor and fever. Since then, she would have severe con-vulsive fits and retarded the development and sitting, standing and walking were impossible till death of the pneumonia at the age of 13 months.

The neuropathologic findings consisted of : 1) diffuse scars of the central white matter, 2) mantle sclerosis in especially anterior and posterior central gyri, 3) incomplete tissue necrosis (ischaemic ne-crosis) in the Ammon's horn and thalamus (Nucl. lat.), 4) retrograde degeneration in the thalamus (Nucl. lat.), 5) central cerebellar lobules atrophy, 6) chronic recurrent brain edema in the circum-ference of thalamic blood vessels (Nucl. med.).