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Therapeutic Efficacy of Chronic Beta-blockade in Idiopathic Dilated Cardiomyopathy Tsutomu Yoshikawa 1 , Shunnosuke Handa 1 , Makoto Akaishi 1 , Sumihisa Abe 1 , Yasushi Asakura 1 , Soushin Inoue 1 , Hideo Mitamura 1 , Satoshi Ogawa 1 1Cardiopulmonary Division, Department of Medicine, Keio University School of Medicine Keyword: 拡張型心筋症 , うっ血性心不全 , β遮断薬 , dilated cardiomyopathy , congestive heart failure , beta-blocker pp.261-266
Published Date 1994/3/15
DOI https://doi.org/10.11477/mf.1404900831
  • Abstract
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This study investigated the therapeutic efficacy of chronic beta-blockade in idiopathic dilated cardio-myopathy (DCM). Seventeen patients with DCM received beta-blocker (metoprolol in 9, and nipradilol in 8, group B) for a mean of 19 months (3-35). Eight patients with DCM not given beta-blocker served as control (group C). New York Heart Association func-tional class improved in group B, but not in group C. The left ventricular end-diastolic dimension decreased from 6.8±0.9 cm to 6.2±0.7 cm in group B (p<0.01). End-systolic dimension also decreased from 5.8±0.9 cm to 4.8±0.8 cm (p<0.01).


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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