Japanese

The clinical significance ofΔVO2/work load as a new parameter of exercise tolerance Hisashi Matsumoto 1 , Toshikazu Mizuno 1 , Masashi Yamashita 1 , Mikio Azuma 1 , Shoichi Shinohara 1 , Keitaku Kim 1 , Jyoichi Ohno 1 , Kazumi Ishida 2 1Division of Cardiology, Mimihara General Hospital 2Division of Physiology, Mimihara General Hospital pp.987-991
Published Date 1988/9/15
DOI https://doi.org/10.11477/mf.1404205326
  • Abstract
  • Look Inside

Progressive bicycle exercise test was performed in 27 patients with chronic heart disease, and ΔVO2/ work load (ml/min/watt) was measured in order to evaluate exercise tolerance. ΔVO2/work load was calculated by the following two formulas, and each ΔVO2/work load was expressed as ΔVO2 (max) and VO2 ( 5 min) as shown under.

ΔVO2(max)=VO2 (max)-VO2 (rest)/work load at max.stage

ΔVO2(5 min)=VO2 (max)-VO2 (rest)/work load at 5 min

Simultaneously cardiac output (CO) was measured by Fick's principle and ACO/work load (ml/min/ watt) was calculated.

VO2 (max) correlated with VO2 (max) in 27 cardiac patients (r= 0.69, p<0.01). Respiratory compensatory threshold (RCT) was shown in eighteen patients, and in thisroup ΔVO2 (max) and AVO2( 5 min) correlated with VO2 (max) respectively (r= 0.80, p<0.01 ; r= 0. 68, p <0. 02).

ΔVO2( 5 min) decreased progressively as New York Heart Association functional classification advanced (Class I , 12. 1.± 1. 5 m//min/watt ; Class II , 11. 8 ± 1. 6 ; Class 711, 9. 5 1. 7 ; p<0. 05 between each group other than Class I and ClassII ). ΔVO2 ( 5 min) cor-related with ΔCO/work load (r= 0. 70, p 0. 01).

Thus VO2/work load is one of the important para-meters in order to evaluate exercise tolerance in patients with chronic heart disease.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

関連文献

もっと見る

文献を共有