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A case of tuberculous pericarditis with marked high level of adenosine deaminase (ADA) activity in pericardial effusion Yutaka Okamoto 1 , Masahiko Mori 1 , Katsusuke Omori 2 , Isao Tukahara 3 1Department of Internal Medicine, Matsuyama Shimin Hospital 2Department of Surgery, Matsuyama Shimin Hospital 3Department of Anesthesiology, Matsuyama Shimin Hospital pp.561-564
Published Date 1988/5/15
DOI https://doi.org/10.11477/mf.1404205261
  • Abstract
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 A 71-year-old female was admitted to our hospital because of malaise and weightloss. Echocardiogram disclosed much pericardial effusion. Pericardial aspiration confirmed marked high level of ADA (adenosine deaminase activity), 38.6 IU/l in bloody effusion. Therapeutic trials of tuberculostat resulted in response and she was diagnosed tuberculous pericarditis.

 We once measured ADA in pericardial effusion of carcinomatous pericarditis complicated with lung cancer and ADA value was low, 10.8 IU/l. In the case of pleuritis, it is well known that measurement of ADA in pleural effusion is useful for the differential diagnosis of tuberculous and carcinomatous pleuritis. Namely, high level of ADA in pleural effusion suggests tuberculous pleuritis and comparatively low level of ADA suggests carcionomatous and others. We speculated that same thing might be said in pericarditis and above two cases support our speculation. Of course, we need more cases in number and further study to establish our speculation.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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