Comparison of new standard indocyanine green dye and old one for cardiac output measurement by dye dilution method Ryo Katori 1 , Shuichiro Osato 1 , Kozui Miyazawa 2 , Koichi Taniguchi 3 , Takahisa Uchiyama 4,5 , Katsuichiro Sakai 4,5 1The First Department of Internal Medicine, Kinki University School of Medicine 2Department of Clinical Laboratory, Yamagata University School of Medicine 3The Second Department of Internal Medicine, Tokyo Medical and Dental University School of Medicine 4The Second Department of Internal Medicine, Nihon University School of Medicine pp.83-88
Published Date 1986/1/15
DOI https://doi.org/10.11477/mf.1404204808
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The aim of this study was to compare new stand-ard indocyanine green dye (DG-A) with old one (DG-B) for the measurement of cardiac output by the dye dilution method. DG-A has lower content of NaI than DG-B, so that light absorption will be more increased for DG-A than DG-B and cardiac output must be underestimated when DG-A is used in place of DG-B. The study was performed in 86 cases included various cardiac diseases and volun-teers at 4 separate hospitals in Japan. Cardiac outputs by using DG-A and DG-B very closely correlated with each other (r=0.932, y=1.0695x+0.3566, p<0.001 ). The ratio of DG-A cardiac output to DG-B cardiac output was 1.158±0.116, indicating a quite agreement with the value of 1.166±0.022 which was the ratio of the absorption coefficient of two dye solutions. Thus, it is concluded that a pro-posed correction coefficient of 1.16 which was pub-lished previously will be suitable for the dye dilu-tion method when new dye is applied.

Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.


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