Small Intestinal Lesions in Patients with Familial Mediterranean Fever Detected by Endoscopy Tomoya Iida 1 , Maki Miyakawa 2 , Masanao Nasuno 2 , Hiroki Tanaka 2 , Yuichiro Yoshida 3 , Koichi Kurahara 3 , Kensuke Asakura 4 , Shunichi Yanai 4 , Takayuki Matsumoto 4 , Hiroshi Nakase 1 1Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan 2Inflammatory Bowel Diseases Center, Sapporo-Kosei General Hospital, Sapporo, Japan 3Division of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan 4Division of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan Keyword: 炎症性腸疾患 , 家族性地中海熱 , MEFV遺伝子 pp.526-531
Published Date 2019/4/25
DOI https://doi.org/10.11477/mf.1403201628
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 FMF(familial mediterranean fever)is a hereditary autoinflammatory disease characterized by periodic fevers and pain induced by serositis of the abdomen, chest, and other areas. Although it is rare for FMF to present with disorders of the gastrointestinal mucosa, reports have detailed cases complicated by gastrointestinal lesions that resemble inflammatory bowel disease. Here we summarize the reports of FMF-related small bowel lesions and discuss the endoscopic characteristics of these lesions. Most of the small bowel lesions observed in patients with FMF were aphthae, erosions, abscesses, or edema, but more cases are needed to fully confirm the endoscopic characteristics of FMF small bowel lesions.

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