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Clinical Characteristics of Cryptogenic Multifocal Ulcerous Stenosing Enteritis(CMUSE) Manabu Nagayama 1 , Tomonori Yano 1 , Hirotsugu Sakamoto 1 , Keijiro Sunada 1 , Hironori Yamamoto 1 1Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan Keyword: PG関連腸症 , 膜様狭窄 , diaphragm disease , PLA2G4A遺伝子変異 , cPLA2α欠乏 pp.1458-1466
Published Date 2017/10/25
DOI https://doi.org/10.11477/mf.1403201199
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 CMUSE(cryptogenic multifocal ulcerous stenosing enteritis)is a rare disorder characterized by chronic or relapsing subileus that results from multiple fibrous stenoses and multiple shallow ulcers of the small intestine. The lesions are mainly concentric short stenoses, and the ulcers/fibrosis are restricted to the mucosa and submucosa. Systemic corticosteroid therapy or surgical resection is the treatment of choice, and endoscopic balloon dilation could be an alternative for avoiding surgery. Although prostaglandin metabolism is reportedly associated with CMUSE pathogenesis, the association has not yet been confirmed, and further analyses with larger patient numbers are required.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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