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Magnifying Endoscopic Diagnosis for IBD:UC-associated Colorectal Cancer Yasushi Iwao 1 , Masayuki Shimoda 2 , Syuji Mikami 3 , Kaori Kameyama 3 , Makoto Naganuma 4 , Shinta Mizuno 4 , Haruhiko Ogata 4 , Takanori Kanai 4 , Kouji Okabayashi 5 , Hirotoshi Hasegawa 5 , Yuko Kitagawa 5 , Yoshinori Sugino 1 1Center for Preventive Medicine, Keio University Hospital, Tokyo 2Department of Pathology, Keio University School of Medicine, Tokyo 3Department Diagnostic Pathology, Keio University Hospital, Tokyo 4Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 5Department of Surgery, Keio University School of Medicine, Tokyo Keyword: 潰瘍性大腸炎 , 大腸癌 , 異型上皮 , 拡大内視鏡 , 画像強調内視鏡 pp.690-699
Published Date 2016/5/24
DOI https://doi.org/10.11477/mf.1403200630
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 An increased risk of UCAC(ulcerative colitis-associated cancer)has been reported in patients with long-standing ulcerative colitis, and cancer surveillance in such patients is recommended. However, it is difficult to detect early lesions developing from flat mucosa with active inflammation. Selection of high-risk groups and careful examination using magnifying endoscopy and/or image-enhanced endoscopy are essential for detecting early lesions of UCAC, IENs(especially intraepithelial neoplasms). Nearly 40% of IENs are flat in reddish areas. The IVV pit pattern is the most frequent pattern ; however, the round pit pattern was observed in 70% of the flat lesions. Magnifying endoscopic observation of reddish areas may assist in early detection of flat lesions of UCAC/dysplasia.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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