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Endoscopic Diagnosis of UC-associated Colorectal Cancer and Dysplasia with Differential Diagnosis between Sporadic Adenoma Yasushi Iwao 1 , Nagamu Inoue 1 , Katsuyoshi Matsuoka 2 , Tadakazu Hisamatsu 2 , Susumu Okamoto 2 , Tomoharu Yajima 2 , Takanori Kanai 2 , Toshifumi Hibi 2 , Hiroyuki Imaeda 1 , Haruhiko Ogata 1 , Takashi Endo 3 , Yoshiyuki Ishii 3 , Hirotoshi Hasegawa 3 , Yoshinori Sugino 4 , Syuji Mikami 5 , Makio Mukai 5 1Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo 2Department of Internal Medicine, Keio University School of Medicine, Tokyo 3Department of Surgery, Keio University School of Medicine, Tokyo 4Department of Radiology, Keio University School of Medicine, Tokyo 5Department of Pathology, Keio University School of Medicine, Tokyo Keyword: 潰瘍性大腸炎 , 大腸癌 , 異型上皮 , 拡大内視鏡 , pit pattern pp.849-858
Published Date 2010/4/30
DOI https://doi.org/10.11477/mf.1403101941
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 An increased risk of ulcerative colitis-associated cancer(UCAC)has been reported in patients with long-standing ulcerative colitis and cancer surveillance is recommended. It is essential for the early detection of UCAC to understand the characteristics of the endoscopic findings of those lesions. We analyzed endoscopic features of 55 lesions of early type UCAC and dysplasia. 42 lesions(76.4%)were protruded type, 13 lesions(23.6%)were superficial type, such as flat and/or depressed type. On magnifying endoscopy, all lesions showed tumorous pit patterns of Kudo' criteria. We showed type IVV is the main pit pattern among the neoplastic lesions associated with UC, especially among protruded lesions. On the other hand, type IIIL/IIIB pit patterns are dominant among flat lesions. However, further studies are necessary for establishing the role of magnifying endoscopy in the early diagnosis of UCAC and dysplasia.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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