Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
- サイト内被引用 Cited by
要旨●胃底腺型胃癌の通常内視鏡所見について検討した.胃底腺型胃癌の典型例はH. pylori感染の有無にかかわらず,萎縮性変化のない胃底腺粘膜に発生し,褪色調,粘膜下腫瘍(SMT)様の隆起性病変,樹枝状の拡張血管を呈する.また,胃底腺型胃癌の中には病変内に限局する色素沈着を伴うものが存在し,病理組織では腫瘍腺管内に好酸性物質が貯留しており,その内部には褐色調の微細顆粒状沈着物を認め,色素沈着の原因と考えられた.この色素沈着は胃底腺型胃癌の特徴のひとつである可能性があり,胃底腺粘膜内の限局する色素沈着に注目することにより,胃底腺型胃癌の早期発見の契機になる可能性が考えられた.
We investigated endoscopic features of gastric adenocarcinoma of fundic gland type using conventional endoscopy. Its characteristic features are as follows : 1)it develops on non-atrophic fundic gland mucosa of the stomach, regardless of the presence or absence of Helicobacter pylori infection ; 2)it appears as an area of discoloration with 3)submucosal tumor-shape; and 4)it exhibits dilated superficial vessels with branching architecture. Some of these adenocarcinomas may be accompanied by pigmentation localized within the lesion. Histologic examination of such pigmented lesions revealed accumulation of eosinophilic substances within tumor glands, with brownish microgranular depositions, which presumably account for the pigmentation. This pigmentation may be a characteristic feature of gastric adenocarcinoma of fundic gland type, and focusing on such pigmentation localized within fundic gland mucosa may enable early detection of the tumor.
Copyright © 2015, Igaku-Shoin Ltd. All rights reserved.