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Japanese

Endoscopic Features of Gastric Adenocarcinoma of Fundic Gland Type Masahiro Nakagawa 1 , Makoto Abe 2,3 , Shinichi Takada 4 , Toru Yamabe 2 , Hideaki Kinugasa 2 , Koji Miyahara 2 , Reiji Higashi 2 , Ken Hirao 2 , Tsuneyoshi Ogawa 2 , Masaki Kunihiro 2 , Toshiaki Morito 4 , Koichi Ichimura 4 , Ichiro Yamadori 4 , Hiroyuki Okada 3 , Motowo Mizuno 2,5 1Department of Endoscopy, Hiroshima City Hospital, Hiroshima, Japan 2Department of Internal Medicine, Hiroshima City Hospital, Hiroshima, Japan 3Departments of Gastroenterology and Hepatology and General Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan 4Department of Pathology, Hiroshima City Hospital, Hiroshima, Japan 5Department of Gastroenterology, Kurashiki Central Hospital, Kurashiki, Japan Keyword: 胃底腺型胃癌 , 内視鏡所見 , 胃色素沈着 , 胃黒点・黒斑 pp.1521-1531
Published Date 2015/11/25
DOI https://doi.org/10.11477/mf.1403200468
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 We investigated endoscopic features of gastric adenocarcinoma of fundic gland type using conventional endoscopy. Its characteristic features are as follows : 1)it develops on non-atrophic fundic gland mucosa of the stomach, regardless of the presence or absence of Helicobacter pylori infection ; 2)it appears as an area of discoloration with 3)submucosal tumor-shape; and 4)it exhibits dilated superficial vessels with branching architecture. Some of these adenocarcinomas may be accompanied by pigmentation localized within the lesion. Histologic examination of such pigmented lesions revealed accumulation of eosinophilic substances within tumor glands, with brownish microgranular depositions, which presumably account for the pigmentation. This pigmentation may be a characteristic feature of gastric adenocarcinoma of fundic gland type, and focusing on such pigmentation localized within fundic gland mucosa may enable early detection of the tumor.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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