Patient Characteristics and Indication for Endoscopic Submucosal Dissection in Elderly Patients with Early Gastric Cancer Koji Miyahara 1 , Masahiro Nakagawa 1,2 , Yoshiyasu Kono 1,3 , Tetsu Hirata 1 , Yuka Obayashi 1 , Tatsuhiro Gotoda 1 , Saimon Takada 1 , Yuki Moritou 1 , Ken Hirao 1 , Masaki Kunihiro 1 , Motowo Mizuno 4 , Hiroyuki Okada 3 1Department of Internal Medicine, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan 2Department of Endoscopy, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan 3Department of Gastroenterology & Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan 4Department of Gastroenterology, Kurashiki Central Hospital, Okayama, Japan Keyword: 高齢者 , 早期胃癌 , ESD , 適応 , 全身状態 pp.1507-1515
Published Date 2020/11/25
DOI https://doi.org/10.11477/mf.1403202188
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 To help determine the indications for ESD(endoscopic submucosal dissection)in elderly patients with early gastric cancer, we investigated the relevance of patients' background characteristics with their prognosis after ESD. In 199 patients aged ≧80 years with early gastric cancer treated with ESD, we found that performance status, PN(Iprognostic nutritional index), comorbidity of cirrhosis, and estimated glomerular filtration rate were significantly associated with overall survival, suggesting that these factors may help define the indications for ESD. With a cutoff value of PNI 45.5, a significant difference in overall survival was observed. In addition, certain comorbidities were found associated with adverse events after ESD, and such factors should also be considered when defining the indications for ESD.

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