Early Gastric Cancer Consist of Well Differentiated Tubular Adenocarcinoma with Solid Type Carcinoma Showing Neuroendocrine Differentiation, Report of a Case Shigetaka Tounou 1 , Yasushi Morita 1 , Miki Miura 1 , Nobukazu Nakamura 1 , Ryouji Furuta 1 , Kazuhito Mita 2 , Hideto Itoh 2 , Shigeru Okamoto 3 1Department of Gastroenterology, Shin-Tokyo Hospital, Matsudo, Japan 2Department of Surgery, Shin-Tokyo Hospital, Matsudo, Japan 3Department of Pathology, Shin-Tokyo Hospital, Matsudo, Japan Keyword: 早期胃癌 , 胃内分泌細胞癌 , 高分化腺癌 , 充実型低分化腺癌 pp.1588-1595
Published Date 2012/9/25
DOI https://doi.org/10.11477/mf.1403113605
  • Abstract
  • Look Inside
  • Reference
  • Cited by

 80-year-old women visited our hospital to receive treatment for the early gastric cancer.

 X-ray examination showed a protruded lesion 2cm in diameter on the posterior wall of the middle portion of the stomach. Endoscopic findings showed a type 0-I lobular lesion with a smooth surface, and no signs of submucosal invasion. Endoscopic resection(ESD)was carried out without complication. Histopathological examination showed a well differentiated tubular adenocarcinoma with a poorly differentiated tubular adenocarcinoma, and also showed submucosal invasion, lymphatic invasion, and vascular invasion. Additional surgical resection was performed, and histopathological examination showed a regional lymph node metastasis. Immunohistological examinations(chronogranin-A, synaptophysin, CD56)showed neuroendocrine differentiation in the deep layer of the early gastric cancer which caused lymphatic invasion and vascular invasion. Final histopathological diagnosis was described as early gastric cancer, 0-I, tub1 with solid type carcinoma showing neuroendocrine differentiation, pT1(SM2 : 590μm), ly1, v2, N1, M0, Stage IB.

Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院