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Peutz-Jeghers Syndrome Associated with Carcinoma of the Descending Colon, Report of a Case Hideo Takahashi 1 , Hideyo Ishida 1 , Sadao Anazawa 1 , Masaya Suzuki 1 , Kenji Sakurai 1 1The First Department of Surgery, Jikei University, School of Medicine pp.321-326
Published Date 1986/3/25
DOI https://doi.org/10.11477/mf.1403110164
  • Abstract
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 A 42 year-old man, who had perioral and digital skin pigmentations, complained of low abdominal pain and constipation. Barium enema study disclosed multiple polyps in the small and large intestine, and long stricture with irregularity of the descending colon. Colonoscopic polypectomy of the rectal polyps was done, followed by surgery with some procedures of partial jejunal resection, left hemicolectomy, and transenteric polypectomy. Surgical specimen were histologically examlned in detail which were found that each polyp was hemartoma as one of Peutz-Jeghers syndromes without co-existence of carcinoma in situ, and a colonic tumor was well differentiated adenocarcinoma with subserosal invasion with mucoid formation. Review of the literature shows that there are some evidence genetically easy to develop the tumor in the colon and rectum including other organs, but still colonic carcinogenesis of Peutz-Jeghers syndrome is unknown.


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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