Reactive Lymphoid Hyperplasia (RLH)-like Lesion of the Gallbladder, Report of a Case Takashi Hayasaka 1 , Fumio Ishizaka 1 , Yutaka Watanabe 1 , Shin-ichi Yasuura 1 1Department of Internal Medicine, Hakodate Chuo Hospital Keyword: 胆囊 , RLH , リンパ腫 pp.1107-1111
Published Date 1992/9/25
DOI https://doi.org/10.11477/mf.1403109990
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 A 43-year-old woman was admitted to Hakodate Chuo Hospital because of a polypoid lesion of the gallbladder. A hyperechoic mass in the gallbladder was identified by ultrasonography. The resected specimen showed a hemispherical tumor with central depression. Histopathologically, the tumor consisted of three areas: 1) RLH-like lesion in the surrounding area, which was composed of proliferation of lymphatic nodules, abundant collagen fibers and plasma cells. 2) Atypical lymphocytic cell proliferation in the central are aaccompanied by plasma cells with disappearance of lymphatic nodules. 3) Diffuse atypical lymphocytic proliferation in the upper area. These three areas may be contiguous. It is suggested that this RLH-like lesion might be premalignant. This case was thought to be worth reporting because of the relationship between RLH and malignant lymphoma.

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