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Progress in the Diagnosis of Gastric UIcer in the Last Twenty Years Toshihiko Saito 1 , Minoru Kawaguchi 1 , Yoji Harada 1 1Department of Internal Medicine, Tokyo Medical College pp.129-134
Published Date 1985/2/25
DOI https://doi.org/10.11477/mf.1403109685
  • Abstract
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 The diagnosis of gastric ulcer has made great progress along with the advances in the development of endoscopic instruments. In particular, diagnosis based on gastric biopsy has become indispensable for differential diagnosis. It is especially important to distinguish gastric ulcer from early gastric cancer and malignant lymphoma of the stomach.

 Recently, the incidence of gastric linear ulcers having typical deformity has decreased. There has also been a tendency towards a reduction, year after year, in the number of cases requiring surgical treatment. These may be attributable to early treatment based on the advanced diagnosis of gastric ulcer as well as on the general improvement in life environment. In addition, the remarkable contribution of drug therapy must not be overlooked. For example, histamine H2-receptor antagonists have come into widespread clinical use, with consequent improvement in the healing of gastric ulcers.

 However, satisfactory and effective means against the recurrence of gastric ulcer remain to be studied. Furthermore, clarification of the gastric mucosal defensive mechanism is still under investigation. It is desirable to establish an effective therapeutic model, taking both aggressive and defensive factors into consideration.

 The relationship between acute and chronic gastric ulcers still remains to be a topic for current and future research.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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