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Total Gastric Necrosis Associated with Sepsis, Report of a Case Masayuki Yamamoto 1 , Masaaki Miyamoto 1 , Masahiko Tsujimoto 2 , Kiyoshi Kotoh 2 , Kikushi Katsurada 1 1Department of Emergency Medicine, Osaka Prefectural Hospital 2Department of Pathology, Osaka Prefectural Hospital pp.311-316
Published Date 1988/3/25
DOI https://doi.org/10.11477/mf.1403107964
  • Abstract
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 A 39 year-old woman who camplained of upper abdominal pain after a meal was admitted in a state of shock to our emergency department. She was diagnosed and treated as having acute hemorrhagic pancreatitis. On the 21st day after hospitalization, her general condition had deteriorated because of sepsis, and gastric necrosis with perforation was found. Total gastrectomy was performed. No lesion was found in the esophagus nor the duodenum at operation.

 The entire resected stomach showed severe hemorrhagic necrosis and sloughing of the entire mucosa with a perforation of its upper part. Microscopic examination revealed full thickness necrosis of the gastric wall with marked round cell infiltration. There was no microabscesses. These histologic features were quite different from classical phlegmonous gastritis. The exact cause of gastric necrosis was unknown, but systemic infection and focal hypoperfusion was considered to be a major aggravating factor.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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